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KMID : 0363320000210010100
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Journal of Korean Oriental Internal Medicine
2000 Volume.21 No. 1 p.100 ~ p.107
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Effects of Artemisiae Capillaris Fructus on Experimental Liver Damage by CC/₄
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Lee Chae-Jung
Kim Hyeong-Hwan
Kim Jong-Dae
Kim Cheorl-Ho
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Abstract
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Objective : To investigate the effects of Artemisiae Capillaris Fructus on liver injury induced CC/₄.
Method : Carbon tetrachloride-induced hepatic injury in CC/₄,-treated rats caused changes in the glutamic oxaloacetic transaminase(GOT), glutamic pyruvic transaminase(GPT) and alkaline phosphatase(ALP) activities in the serum.
Result : The Methanol extract of the Artemisiae Capillaris Fructus was found to protect the rats against such changes significantly. Protective activities were shown to be present in ether-soluble and buthanol-soluble fractions prepared from the above methanol extract.
Conclusion : we have examined the detoxyfying effect, one of several medicinal effects of Artemisiae Capillaris Fructus. on liver disorder experimentally induced by CC/₄. as an animal model of liver disorder.
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KEYWORD
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ALP, GOT, GPT, CC/₄
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